113學年材料所-第二週 專題研討課程 演講公告 (113年9月19日)
2024.09.16
2024.09.16
113學年上學期專題討論公告
題目:
從「星星」到奈米：多孔聚乙二醇水凝膠薄膜和奈米片作為多功能感測與奈米製造平台
From “stars” to nano: Porous poly(ethylene glycol) hydrogel films and nanosheets as a versatile platform for sensing and nanofabrication
演講者: Prof. (apl.) Dr. Michael Zharnikov
現職: Professor Emeritus, Heidelberg University
時間: 113年9月19日(四) 下午15:10~16:00
地點: 成功大學成功校區三系館 鋼構區(3F)共同教室A1302演講廳
演講摘要:
Whereas biorepulsive oligo- and poly(ethylene glycols) (OEGs and PEGs) are widely used for different applications, they have not been utilized yet as materials for free-standing nanosheets. In this context, I discuss the fabrication and potential applications of novel PEG hydrogel films and nanosheets, prepared by thermally activated crosslinking of amine- and epoxy-terminated, star-branched PEG oligomers and abbreviated as PHFs and PHNs, respectively. These systems possess a variety of useful properties, including tunable thickness (4-300 nm) and porosity (7-70 nm), bioinertness, robustness, and extreme elasticity. They can serve as a basis for composite materials (by loading with nanoparticles, fullerenes, etc.), advanced nanofabrication, and lithography, using electron irradiation and ultraviolet light as writing tools (different characters of the fabricated patterns). They can also be used as bioinert supports for high-resolution transmission electron microscopy and highly sensitive elements in MEMS, humidity sensors, and moisture-responsive nanoelectronic devices, relying on either optical or resistive transduction technique. The PHFs and PHNs are also able to host protein-specific receptors, providing, at the same time, a protein-repelling and humidity-responsive matrix with flexible porosity. Further applications of PHFs and PHNs include highly selective and sensitive, electrochemical DNA sensing, relying on immobilization of suitable, single-strand DNA probes into the 3D PEG matrix over controlled chemical coupling to free amine or epoxy groups. The concentration of these groups was properly adjusted by setting the composition of the precursors aside from the equilibrium, which, however, did not result in the deterioration of any other film properties. Finally, by introducing gold nanoparticles into the porous matrix of PHFs and PHNs, a novel electrochemical sensor for the detection of hydrogen peroxide was designed, featuring both high sensitivity and selectivity. Even though the above examples span a broad field - from nanoengineering to biosensing, the applications of the PHFs and PHNs are certainly not limited to these examples but can be specifically adapted and extended to other fields, such as tissue engineering and drug delivery, relying on versatility and tunability of these systems.
歡迎各位撥冗參加!!
113學年上學期專題討論公告
題目:
從「星星」到奈米：多孔聚乙二醇水凝膠薄膜和奈米片作為多功能感測與奈米製造平台
From “stars” to nano: Porous poly(ethylene glycol) hydrogel films and nanosheets as a versatile platform for sensing and nanofabrication
演講者: Prof. (apl.) Dr. Michael Zharnikov
現職: Professor Emeritus, Heidelberg University
時間: 113年9月19日(四) 下午15:10~16:00
地點: 成功大學成功校區三系館 鋼構區(3F)共同教室A1302演講廳
演講摘要:
Whereas biorepulsive oligo- and poly(ethylene glycols) (OEGs and PEGs) are widely used for different applications, they have not been utilized yet as materials for free-standing nanosheets. In this context, I discuss the fabrication and potential applications of novel PEG hydrogel films and nanosheets, prepared by thermally activated crosslinking of amine- and epoxy-terminated, star-branched PEG oligomers and abbreviated as PHFs and PHNs, respectively. These systems possess a variety of useful properties, including tunable thickness (4-300 nm) and porosity (7-70 nm), bioinertness, robustness, and extreme elasticity. They can serve as a basis for composite materials (by loading with nanoparticles, fullerenes, etc.), advanced nanofabrication, and lithography, using electron irradiation and ultraviolet light as writing tools (different characters of the fabricated patterns). They can also be used as bioinert supports for high-resolution transmission electron microscopy and highly sensitive elements in MEMS, humidity sensors, and moisture-responsive nanoelectronic devices, relying on either optical or resistive transduction technique. The PHFs and PHNs are also able to host protein-specific receptors, providing, at the same time, a protein-repelling and humidity-responsive matrix with flexible porosity. Further applications of PHFs and PHNs include highly selective and sensitive, electrochemical DNA sensing, relying on immobilization of suitable, single-strand DNA probes into the 3D PEG matrix over controlled chemical coupling to free amine or epoxy groups. The concentration of these groups was properly adjusted by setting the composition of the precursors aside from the equilibrium, which, however, did not result in the deterioration of any other film properties. Finally, by introducing gold nanoparticles into the porous matrix of PHFs and PHNs, a novel electrochemical sensor for the detection of hydrogen peroxide was designed, featuring both high sensitivity and selectivity. Even though the above examples span a broad field - from nanoengineering to biosensing, the applications of the PHFs and PHNs are certainly not limited to these examples but can be specifically adapted and extended to other fields, such as tissue engineering and drug delivery, relying on versatility and tunability of these systems.
歡迎各位撥冗參加!!